UT-GPCR005 Fluorescence anisotropy time-series of competition binding between unlabeled ligands of M1 muscarinic acetylcholine receptor and TAMRA labeled UR-MK342

Laasfeld, Tõnis; Bláhovcová, Hana; Hollo, Kaspar; Rinken, Ago; Veiksina, Santa
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UT-GPCR005 Fluorescence anisotropy time-series csv files.zip182.4Kbcsv files of kinetic traces of highest used concentrations of various unlabeled ligands. Each ligand is in a separate file.
UT-GPCR005 Fluorescence anisotropy time-series Prism file.zip610.1KbGraphpad Prism file of kinetic traces of highest used concentrations of various unlabeled ligands.
README.txt2.740KbREADME
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Date
2026-03-26
URI
https://datadoi.ee/handle/33/738
https://doi.org/10.23673/re-572
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Abstract
Fluorescence anisotropy time-series of competition ligand binding between unlabeled competitors of M1 muscarinic acetylcholine receptor and TAMRA labeled UR-MK342. The dataset contains kinetic traces of UR-MK259, UR-SK-75, McN-A-343, UR-SK-59, Scopolamine, Telenzepine, 4-DAMP, Carbachol, Pilocarpine, Clozapine, Pirenzepine, Atropine, Acetylcholine, Trospium, NMS, Arecoline, W84, Xanomeline and LY2119620 in competition with TAMRA labeled muscarinic acetylcholine recepotor fluorescent ligand UR-MKK342. The dataset also contains non-linear regression fits of these time-series. Details of experimental setup are given in the related publication....  Show more  Show less
Keyword
Allosteric modulator; Bitopic ligand; Fluorescence polarization; G protein-coupled receptor; Kinetic analysis; LY2119620
Item type
info:eu-repo/semantics/dataset
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info:eu-repo/semantics/openAccess
Except where otherwise noted, this item's license is described as info:eu-repo/semantics/openAccess