UT-GPCR001 microscopy of ligand binding to M4 muscarinic receptor in live CHO-K1-hM4 cells

Tahk, Maris-Johanna; Torp, Jane; Ali, Mohammed A.S.; Fishman, Dmytro; Parts, Leopold; Grätz, Lukas; Müller, Christoph; Keller, Max; Veikšina, Santa; Laasfeld, Tõnis; Rinken, Ago
NameSizeDescription
200130_183419_CHO-K1-hM4R-UR-CG072-competition_full.zip4.172Gb
200131_180737_CHO-K1-hM4R-UR-CG072-competition_full.zip4.206Gb
200202_154516_CHO-K1-hM4R-UR-CG072-competition_full.zip4.195Gb
200203_174647_CHO-K1-hM4R-UR-CG072-competition_full.zip2.087Gb
200923_171034_CHO-K1-hM4R-UR-CG072-saturation_full.zip4.146Gb
200924_180945_CHO-K1-hM4R-UR-CG072-saturation.zip4.147Gb
210602_182400-CHO-K1-hM4R-UR-CG072-competition_full.zip5.994Gb
210608_162557_CHO-K1-hM4R-UR-CG072-competition_full.zip5.996Gb
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200908_190941_CHO-K1-hM4R-UR-CG072-competition_full.zip6.262Gb
200909_190335_CHO-K1-hM4R-UR-CG072-competition_full.zip6.267Gb
200910_191627_CHO-K1-hM4R-UR-CG072-competition_full.zip6.269Gb
210621_162328_CHO-K1-hM4R-and-CHO-K1-UR-CG072-saturation.zip8.289Gb
200205_134344_CHO-K1-hM4R-UR-CG072-kinetics_full.zip11.78Gb
200201_151446_CHO-K1-hM4R-UR-CG072-kinetics_full.zip14.39Gb
200204_143804_CHO-K1-hM4R-UR-CG072-kinetics_full.zip14.58Gb
210607_192054_CHO-K1-hM4R-UR-CG072-competition_full.zip6.002Gb
README.txt3.213Kb
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Date
2022
URI
https://datadoi.ee/handle/33/432
https://doi.org/10.23673/re-306
Metadata
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Abstract
The "UT-GPCR001 microscopy of ligand binding to M4 muscarinic receptor in live CHO-K1-hM4 cells" dataset contains the raw microscopy images of the experiments along with images processed using the random forest algorithm and U-Net3 based deep convolutional neural networks for cell segmentation from bright-field images. The dataset contains experiments with a fluorescence ligand UR-CG072 and multiple M4 muscarinic receptor ligands. The dataset contains binding kinetic, fluorescence ligand saturatttion and competition type experiments....  Show more  Show less
Keyword
bright-field microscopy; fluorescence microscopy; GPCR; M4 muscarinic receptor; CHO-K1; UR-CG072; deep convolutional neural networks
Item type
info:eu-repo/semantics/dataset
Collections
info:eu-repo/semantics/openAccess
Except where otherwise noted, this item's license is described as info:eu-repo/semantics/openAccess