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1 to 10 of 11 Results

Data for Nanoformulated bisdemethoxycurcumin does not ameliorate pathology or cognitive impairment in 5xFAD transgenic miceEmbargoed Jul 3, 2026 Hickey, Miriam A., 2026, "Data for Nanoformulated bisdemethoxycurcumin does not ameliorate pathology or cognitive impairment in 5xFAD transgenic mice", https://doi.org/10.23673/HKYC8R, DATADOI, V1, UNF:6:fnILGjjIuosqDx0MeXewgQ== [fileUNF] Dementia and dementia-related diseases are a growing societal burden, and they remain largely incurable. Antibody therapies are very costly and their limited accessibility and efficacy underscore the significant continuing importance of small molecule therapeutics. Curcuminoids are of great interest in neurodegenerative diseases, in particular in A...
High-dose levodopa-associated peripheral neuropathy and glial alterations in stressed mice: Protective effects of Vitamin B12Embargoed Jun 25, 2026 Hickey, Miriam A., 2026, "High-dose levodopa-associated peripheral neuropathy and glial alterations in stressed mice: Protective effects of Vitamin B12", https://doi.org/10.23673/4C6FP0, DATADOI, V1, UNF:6:sy1RAInG23Yi0J3DWcYAEQ== [fileUNF] Peripheral neuropathy (PN) is a common but understudied non-motor symptom of Parkinson’s disease (PD), and its underlying mechanism remains unclear. Although L-DOPA is the primary treatment for motor symptoms of PD, chronic high-dose exposure may contribute to PN. Using stressed but otherwise healthy mice, we found that high-dose L-DOPA increased c...
Sequence data of body site-specific microbiota during pregnancy Oct 20, 2025 Mändar, Reet; Kõljalg, Siiri; Štšepetova, Jelena, 2025, "Sequence data of body site-specific microbiota during pregnancy", https://doi.org/10.23673/RE-549, DATADOI, V1 The dataset comprises a total of 443 samples collected from 105 pregnant women. It contains sequence data derived from clinical material, obtained through 16S rRNA gene sequencing of DNA extracted from the following sample types: 85 vaginal, 84 cervical, 105 urine, 85 oral and 84 rectal samples.
Sequence data of HUMB collection 1.0 Aug 6, 2025 Mändar, Reet; Rööp, Tiiu, 2025, "Sequence data of HUMB collection 1.0", https://doi.org/10.23673/RE-536, DATADOI, V1 Human Microbiota Biobank (HUMB) at University of Tartu, Estonia, was established to support and promote research activities in the field of human microbiota. The collection contains more than 20,000 bacterial strains, both lactic acid bacteria and opportunistic bacteria. The dataset contains sequence data of a portion of the strains.
Mother and child stool bacteriomes: links to maternal gestational diabetes and atopic dermatitis in 1–2-years-old children Apr 28, 2025 Alnek, Kristi; Bärenson, Anu; Aasmets, Oliver; Janson, Helis; Talja, Ija; Laht, Brita; Vorobjova, Tamara; Kirss, Anne; Cinek, Ondrej; Uibo, Raivo; Tagoma, Aili; HEDIMED Investigators group, 2025, "Mother and child stool bacteriomes: links to maternal gestational diabetes and atopic dermatitis in 1–2-years-old children", https://doi.org/10.23673/RE-512, DATADOI, V1 This file contains reads based on ASV data of the gut bacteriomes of mothers with and without GDM and those of their children (1-2 years old) resulting from the pregnancies.
Research data for Early trigeminal and sensory impairment and lysosomal dysfunction in accurate models of Wolfram syndrome Dec 13, 2024 Hickey, Miriam, 2024, "Research data for Early trigeminal and sensory impairment and lysosomal dysfunction in accurate models of Wolfram syndrome", https://doi.org/10.23673/RE-495, DATADOI, V1 We present here data from our paper Early trigeminal and sensory impairment and lysosomal dysfunction in accurate models of Wolfram syndrome. We include data underlying all figures and tables. Research data for publicly available data can be found as cited in README file.
Levodopa impairs lysosomal function in sensory neurons in vitro Sep 16, 2024 Hickey, Miriam, 2024, "Levodopa impairs lysosomal function in sensory neurons in vitro", https://doi.org/10.23673/RE-477, DATADOI, V1 Parkinson’s disease (PD) is one of the most common chronic, degenerative brain diseases worldwide. Patients are diagnosed on the basis of slowness of movement and/or tremor and/or stiffness. However, many symptoms that are not movement related are now well recognized. Patients show changes in skin sensation, and the vast majority of patients show l...
Antibodies against Clostridium butyricum in the children of mothers at risk for gestational diabetes Jun 20, 2024 Peterson, Celeste; Tagoma, Aili; Alnek, Kristi; Bärenson, Anu; Vorobjova, Tamara; Talja, Ija; Janson, Helis; Kirss, Anne; Kõljalg, Siiri; Sinkkonen, Aki; Roslund, Marja Irmeli; HEDIMED Investigator group; Uibo, Raivo, 2024, "Antibodies against Clostridium butyricum in the children of mothers at risk for gestational diabetes", https://doi.org/10.23673/RE-470, DATADOI, V1 Clostridium butyricum T2F3 specific IgA and IgG antibody response detection using immunoblot.
Sequenced placenta, serum and urine miRNomes of three healthy pregnancies Jul 11, 2022 Laan, Maris; Inno, Rain, 2022, "Sequenced placenta, serum and urine miRNomes of three healthy pregnancies", https://doi.org/10.23673/RE-348, DATADOI, V1 Sequenced miRNomes of the placenta, serum, and urine samples from three healthy pregnant females. Samples are collected from the third trimester.
Dynamics of hepatitis C epidemic among people living with HIV in Estonia based on Estonian HIV cohort study Jul 16, 2021 Kase, Kerstin; Avi, Radko; Toompere, Karolin; Rajasaar, Heli; Pauskar, Merit; Soodla, Pilleriin; Jõgeda, Ene-Ly; Zilmer, Kai; Lutsar, Irja; Huik, Kristi, 2021, "Dynamics of hepatitis C epidemic among people living with HIV in Estonia based on Estonian HIV cohort study", https://doi.org/10.23673/RE-290, DATADOI, V1 Materials to Dynamics of hepatitis C epidemic among people living with HIV in Estonia based on Estonian HIV cohort study

Data for Nanoformulated bisdemethoxycurcumin does not ameliorate pathology or cognitive impairment in 5xFAD transgenic miceEmbargoed

Jul 3, 2026

Hickey, Miriam A., 2026, "Data for Nanoformulated bisdemethoxycurcumin does not ameliorate pathology or cognitive impairment in 5xFAD transgenic mice", https://doi.org/10.23673/HKYC8R, DATADOI, V1, UNF:6:fnILGjjIuosqDx0MeXewgQ== [fileUNF]

Dementia and dementia-related diseases are a growing societal burden, and they remain largely incurable. Antibody therapies are very costly and their limited accessibility and efficacy underscore the significant continuing importance of small molecule therapeutics. Curcuminoids are of great interest in neurodegenerative diseases, in particular in A...

High-dose levodopa-associated peripheral neuropathy and glial alterations in stressed mice: Protective effects of Vitamin B12Embargoed

Jun 25, 2026

Hickey, Miriam A., 2026, "High-dose levodopa-associated peripheral neuropathy and glial alterations in stressed mice: Protective effects of Vitamin B12", https://doi.org/10.23673/4C6FP0, DATADOI, V1, UNF:6:sy1RAInG23Yi0J3DWcYAEQ== [fileUNF]

Peripheral neuropathy (PN) is a common but understudied non-motor symptom of Parkinson’s disease (PD), and its underlying mechanism remains unclear. Although L-DOPA is the primary treatment for motor symptoms of PD, chronic high-dose exposure may contribute to PN. Using stressed but otherwise healthy mice, we found that high-dose L-DOPA increased c...

Sequence data of body site-specific microbiota during pregnancy

Oct 20, 2025

Mändar, Reet; Kõljalg, Siiri; Štšepetova, Jelena, 2025, "Sequence data of body site-specific microbiota during pregnancy", https://doi.org/10.23673/RE-549, DATADOI, V1

The dataset comprises a total of 443 samples collected from 105 pregnant women. It contains sequence data derived from clinical material, obtained through 16S rRNA gene sequencing of DNA extracted from the following sample types: 85 vaginal, 84 cervical, 105 urine, 85 oral and 84 rectal samples.

Sequence data of HUMB collection 1.0

Aug 6, 2025

Mändar, Reet; Rööp, Tiiu, 2025, "Sequence data of HUMB collection 1.0", https://doi.org/10.23673/RE-536, DATADOI, V1

Human Microbiota Biobank (HUMB) at University of Tartu, Estonia, was established to support and promote research activities in the field of human microbiota. The collection contains more than 20,000 bacterial strains, both lactic acid bacteria and opportunistic bacteria. The dataset contains sequence data of a portion of the strains.

Mother and child stool bacteriomes: links to maternal gestational diabetes and atopic dermatitis in 1–2-years-old children

Apr 28, 2025

Alnek, Kristi; Bärenson, Anu; Aasmets, Oliver; Janson, Helis; Talja, Ija; Laht, Brita; Vorobjova, Tamara; Kirss, Anne; Cinek, Ondrej; Uibo, Raivo; Tagoma, Aili; HEDIMED Investigators group, 2025, "Mother and child stool bacteriomes: links to maternal gestational diabetes and atopic dermatitis in 1–2-years-old children", https://doi.org/10.23673/RE-512, DATADOI, V1

This file contains reads based on ASV data of the gut bacteriomes of mothers with and without GDM and those of their children (1-2 years old) resulting from the pregnancies.

Research data for Early trigeminal and sensory impairment and lysosomal dysfunction in accurate models of Wolfram syndrome

Dec 13, 2024

Hickey, Miriam, 2024, "Research data for Early trigeminal and sensory impairment and lysosomal dysfunction in accurate models of Wolfram syndrome", https://doi.org/10.23673/RE-495, DATADOI, V1

We present here data from our paper Early trigeminal and sensory impairment and lysosomal dysfunction in accurate models of Wolfram syndrome. We include data underlying all figures and tables. Research data for publicly available data can be found as cited in README file.

Levodopa impairs lysosomal function in sensory neurons in vitro

Sep 16, 2024

Hickey, Miriam, 2024, "Levodopa impairs lysosomal function in sensory neurons in vitro", https://doi.org/10.23673/RE-477, DATADOI, V1

Parkinson’s disease (PD) is one of the most common chronic, degenerative brain diseases worldwide. Patients are diagnosed on the basis of slowness of movement and/or tremor and/or stiffness. However, many symptoms that are not movement related are now well recognized. Patients show changes in skin sensation, and the vast majority of patients show l...

Antibodies against Clostridium butyricum in the children of mothers at risk for gestational diabetes

Jun 20, 2024

Peterson, Celeste; Tagoma, Aili; Alnek, Kristi; Bärenson, Anu; Vorobjova, Tamara; Talja, Ija; Janson, Helis; Kirss, Anne; Kõljalg, Siiri; Sinkkonen, Aki; Roslund, Marja Irmeli; HEDIMED Investigator group; Uibo, Raivo, 2024, "Antibodies against Clostridium butyricum in the children of mothers at risk for gestational diabetes", https://doi.org/10.23673/RE-470, DATADOI, V1

Clostridium butyricum T2F3 specific IgA and IgG antibody response detection using immunoblot.

Sequenced placenta, serum and urine miRNomes of three healthy pregnancies

Jul 11, 2022

Laan, Maris; Inno, Rain, 2022, "Sequenced placenta, serum and urine miRNomes of three healthy pregnancies", https://doi.org/10.23673/RE-348, DATADOI, V1

Sequenced miRNomes of the placenta, serum, and urine samples from three healthy pregnant females. Samples are collected from the third trimester.

Dynamics of hepatitis C epidemic among people living with HIV in Estonia based on Estonian HIV cohort study

Jul 16, 2021

Kase, Kerstin; Avi, Radko; Toompere, Karolin; Rajasaar, Heli; Pauskar, Merit; Soodla, Pilleriin; Jõgeda, Ene-Ly; Zilmer, Kai; Lutsar, Irja; Huik, Kristi, 2021, "Dynamics of hepatitis C epidemic among people living with HIV in Estonia based on Estonian HIV cohort study", https://doi.org/10.23673/RE-290, DATADOI, V1

Materials to Dynamics of hepatitis C epidemic among people living with HIV in Estonia based on Estonian HIV cohort study

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